What to Do If Your Peptide Doesn’t Fully Dissolve and Appears Cloudy?

Sometimes, when reconstituting peptides, you may notice that the solution appears cloudy or the peptide doesn’t fully dissolve. Don’t worry—this doesn’t necessarily mean the product is bad. Here are a few things you can do:

  1. Be Patient – Some peptides take a bit longer to dissolve. Gently swirl the vial (don’t shake) and give it a few minutes.
  2. Use the Right Solvent – Make sure you’re using the correct diluent. Bacteriostatic water is common, but some peptides dissolve better in acetic acid or sterile saline. Contact your supplier for the recommended solvent.
  3. Warm It Slightly – If the peptide still doesn’t dissolve, you can warm the vial slightly by holding it in your hand or placing it in a warm water bath (27℃-35℃) for a minute or two. This can help stubborn particles dissolve.
  4. Check for Precipitation – If there’s still cloudiness or particles, let the vial sit in the refrigerator for a few hours. If the cloudiness remains, it’s best to consult your supplier for further guidance.

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